Sharing a conceptual model of grid resources and services

Grid technologies aim at enabling a coordinated resource-sharing and problem-solving capabilities over local and wide area networks and span locations, organizations, machine architectures and software boundaries. The heterogeneity of involved resources and the need for interoperability among different grid middlewares require the sharing of a common information model. Abstractions of different flavors of resources and services and conceptual schemas of domain specific entities require a collaboration effort in order to enable a coherent information services cooperation. With this paper, we present the result of our experience in grid resources and services modelling carried out within the Grid Laboratory Uniform Environment (GLUE) effort, a joint US and EU High Energy Physics projects collaboration towards grid interoperability. The first implementation-neutral agreement on services such as batch computing and storage manager, resources such as the hierarchy cluster, sub-cluster, host and the storage library are presented. Design guidelines and operational results are depicted together with open issues and future evolutions.Comment: 4 pages, 0 figures, CHEP 200

EGI: anOpen e-Infrastructure Ecosystem for the Digital European Research Area

Bringing the digital European Research Area (ERA) online means modernising Europe’s research infrastructure by promoting open science through the availability, accessibility and reuse of scientific data and results, the use of web- based tools that facilitate scientific collaboration and ensuring public access to research. As the European Grid Infrastructure (EGI) is the largest European distributed computing infrastructure providing 24/7 access to large scale computing, storage and data resources through a federation of national resource providers, it allows scientists from all disciplines to make the most out of the latest computing technologies for the benefit of their research. This paper describes the methodology and approach for defining EGI’s role in bringing this digital ERA online. The work presented defines the roles and functions of EGI as an open ICT ecosystem, required service redesign, the added value of EGI for the European research communities and demonstrates the role that EGI plays in contributing to the Europe 2020 strategy for social-economic impact

The Strategy of the Commons: Modelling the Annual Cost of Successful ICT Services for European Research

The provision of ICT services for research is increasingly using Cloud services to complement the traditional federation of computing centres. Due to the complex funding structure and differences in the basic business model, comparing the cost-effectiveness of these options requires a new approach to cost assessment. This paper presents a cost assessment method addressing the limitations of the standard methods and some of the initial results of the study. This acts as an illustration of the kind of cost assessment issues high-utilisation rate ICT services should consider when choosing between different infrastructure options. The research is co-funded by the European Commission Seventh Framework Programme through the e-FISCAL project (contract number RI-283449)

The Open Science Commons for the European Research Area

Nowadays, research practice in all scientific disciplines is increasingly, and in many cases exclusively, data driven. Knowledge of how to use tools to manipulate research data, and the availability of e-Infrastructures to support them for data storage, processing, analysis and preservation, is fundamental. In parallel, new types of communities are forming around interests in digital tools, computing facilities and data repositories. By making infrastructure services, community engagement and training inseparable, existing communities can be empowered by new ways of doing research, and new communities can be created around tools and data. Europe is ideally positioned to become a world leader as provider of research data for the benefit of research communities and the wider economy and society. Europe would benefit from an integrated infrastructure where data and computing services for big data can be easily shared and reused. This is particularly challenging in EO given the volumes and variety of the data that make scalable access difficult, if not impossible, to individual researchers and small groups (i.e. to the so-called long tail of science). To overcome this limitation, as part of the European Commission Digital Single Market strategy, the European Open Science Cloud (EOSC) initiative was launched in April 2016, with the final aim to realise the European Research Area (ERA) and raise research to the next level. It promotes not only scientific excellence and data reuse, but also job growth and increased competitiveness in Europe, and results in Europe-wide cost efficiencies in scientific infrastructure through the promotion of interoperability on an unprecedented scale. This chapter analyses existing barriers to achieve this aim and proposes the Open Science Commons as the fundamental principles to create an EOSC able to offer an integrated infrastructure for the depositing, sharing and reuse of big data, including Earth Observation (EO) data, leveraging and enhancing the current e-Infrastructure landscape, through standardization, interoperability, policy and governance. Finally, it is shown how an EOSC built on e-Infrastructures can improve the discovery, retrieval and processing capabilities of EO data, offering virtualised access to geographically distributed data and the computing necessary to manipulate and manage large volumes. Well-established e-Infrastructure services could provide a set of reusable components to accelerate the development of exploitation platforms for satellite data solving common problems, such as user authentication and authorisation, monitoring or accounting

DataTAG Contributing to LCG-0 Pilot Startup

The DataTAG project has contributed to the creation of the middleware distribution constituting the base of the LCG-0 pilot. This distribution has demonstrated the possibility of building an EDG release based on iVDGL/VDT, integrating the GLUE schema and early components of the EDG middleware

The Study of Corporate M&As

Abstract According to the objective and inherent logical coherence of research subject, the thesis is composed of six chapters. The first chapter provides the theoretical background for the thesis. The author reviews and analyzes the western motive theories of corporate M&As so as to clearly recognize them. The commemt and analysis lay a foundation for discussion of the related problem...学位：经济学博士院系专业：经济学院经济系_世界经济学号：B20010901

A Piezoresistive Sensor to Measure Muscle Contraction and Mechanomyography

Measurement of muscle contraction is mainly achieved through electromyography (EMG) and is an area of interest for many biomedical applications, including prosthesis control and human machine interface. However, EMG has some drawbacks, and there are also alternative methods for measuring muscle activity, such as by monitoring the mechanical variations that occur during contraction. In this study, a new, simple, non-invasive sensor based on a force-sensitive resistor (FSR) which is able to measure muscle contraction is presented. The sensor, applied on the skin through a rigid dome, senses the mechanical force exerted by the underlying contracting muscles. Although FSR creep causes output drift, it was found that appropriate FSR conditioning reduces the drift by fixing the voltage across the FSR and provides voltage output proportional to force. In addition to the larger contraction signal, the sensor was able to detect the mechanomyogram (MMG), i.e., the little vibrations which occur during muscle contraction. The frequency response of the FSR sensor was found to be large enough to correctly measure the MMG. Simultaneous recordings from flexor carpi ulnaris showed a high correlation (Pearson's r > 0.9) between the FSR output and the EMG linear envelope. Preliminary validation tests on healthy subjects showed the ability of the FSR sensor, used instead of the EMG, to proportionally control a hand prosthesis, achieving comparable performances

Polarity studies of single polyelectrolyte layers in polyelectrolyte multilayers probed by steady state and life time doxorubicin fluorescence

Hypothesis: Polarity in polyelectrolyte multilayers (PEMs) may vary from the inner to the top layers of the film as the charge compensation of the layers is more effective inside the PEMs than in outer layers. Doxorubicin hydrochloride (DX) is used here to sense polarity at the single polyelectrolyte level inside PEMS. Experimental: DX is complexed electrostatically to a polyanion, either polystyrene sulfonate (PSS) or polyacrylic acid (PAA) and assembled at selected positions in a multilayer of the polyanion and polyally lamine hydrochloride (PAH) as polycation. Local polarity in the layer domain is evaluated through changes in the intensity ratio of the first to second band of spectra of DX (I1/I2 ratio) by steady state flu orescence, and by Lifetime fluorescence. Findings: PAH/PSS multilayers, show a polarity similar to water with DX/PSS as top layer, decreasing to I1/ I2 ratios similar to organic solvents as the number of polyelectrolyte layers assembled on top increases. For PAH/PAA multilayers, polarity values reflect a more polar environment than water when DX/PAA is the top layer, remaining unaltered by the assembly of polyelectrolyte layers on top. Results show that different polar environments may be present in a PEM when considering polarity at the single layer level.Fil: Martinelli, Hernan. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Instituto de Física del Sur. Universidad Nacional del Sur. Departamento de Física. Instituto de Física del Sur; Argentina. Centro de Investigación Cooperativa en Biomateriales; EspañaFil: Tasca, Elisamaria. Centro de Investigación Cooperativa en Biomateriales; España. Università degli Studi di Roma "La Sapienza"; ItaliaFil: Andreozzi, Patrizia. Università degli Studi di Firenze; Dipartimento di Chimica “Ugo Schiff”; Italia. Centro de Investigación Cooperativa en Biomateriales; EspañaFil: Libertone, Sara. Centro de Investigación Cooperativa en Biomateriales; EspañaFil: Ritacco, Hernán Alejandro. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Instituto de Física del Sur. Universidad Nacional del Sur. Departamento de Física. Instituto de Física del Sur; ArgentinaFil: Giustini, Mauro. Università degli Studi di Roma "La Sapienza"; Italia. Università degli Studi di Firenze; Dipartimento di Chimica “Ugo Schiff” ; ItaliaFil: Moya, Sergio Enrique. Centro de Investigación Cooperativa en Biomateriales; España. Università degli Studi di Roma "La Sapienza"; Itali

Multi- to Unilamellar Transitions in Catanionic Vesicles

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Strontium titanate (SrTiO3) mesoporous coatings for enhanced strontium delivery and osseointegration on bone implants

The incorporation of strontium (Sr) in titania enhances surface bioactivity and has a positive effect on pre-osteoblastic cell attachment, proliferation, and differentiation. Strontium titanate mesoporous films (SrTiMFs) with 30% pore volume and a 20% Sr molar content have been prepared by the evaporation induced self-assembly method. SrTiMFs display a large internal surface area available for exchange of Sr, which is released in cell media up to 44% within the first 8 h. SrTiMFs improve attachment of MC3T3-E1 pre-osteoblastic cells, which show larger filopodia and more elongated features than cells attached to plain mesoporous titania films (MTFs). SrTiMFs also display improved cell proliferation and differentiation rates indicating that overall Sr incorporation into mesoporous titania coatings can lead to enhanced osseointegration during the early stages of bone tissue formation.Fil: Escobar, Ane. Centro de Investigación Cooperativa en Biomateriales; EspañaFil: Muzzio, Nicolás Eduardo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Investigaciones Fisicoquímicas Teóricas y Aplicadas. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Instituto de Investigaciones Fisicoquímicas Teóricas y Aplicadas; Argentina. Centro de Investigación Cooperativa en Biomateriales; EspañaFil: Angelome, Paula Cecilia. Comisión Nacional de Energía Atómica. Gerencia del Área de Seguridad Nuclear y Ambiente. Gerencia de Química (CAC); Argentina. Comisión Nacional de Energía Atómica. Centro Atómico Constituyentes; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Bordoni, Andrea Veronica. Comisión Nacional de Energía Atómica. Gerencia del Área de Seguridad Nuclear y Ambiente. Gerencia de Química (CAC); Argentina. Comisión Nacional de Energía Atómica. Centro Atómico Constituyentes; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Martínez, Angel. Centro de Investigación Cooperativa en Biomateriales; EspañaFil: Bindini, Elisa. Centro de Investigación Cooperativa en Biomateriales; EspañaFil: Coy, Emerson. Adam Mickiewicz University. Nanobiomedical Centre; PoloniaFil: Andreozzi, Patrizia. Centro de Investigación Cooperativa en Biomateriales; EspañaFil: Grzelczak, Marek. Donostia International Physic Center; . Basque Foundation for Science; EspañaFil: Moya, Sergio E.. Centro de Investigación Cooperativa en Biomateriales; Españ